Abstract No. 46 Histotripsy of the Stomach Wall During Hepatic Histotripsy in an Acute Swine Model

Histotripsy is a non-invasive focused ultrasound treatment that mechanically destroys liver tumors via cavitation. Tumors in the left hepatic lobe are good candidates for histotripsy due to an ultrasound window unobstructed by ribs. However, this location is adjacent to the stomach which could potentially be injured if included in the treatment prescription. The purpose of this study is to evaluate the safety of hepatic histotripsy when treatment margins extend into either collapsed or gas-filled stomach in an acute swine model.