Abstract No. 194 In Vivo Evaluation of Spectral CT Thermometry for Non-invasive, Real-Time Temperature Monitoring of Thermal Ablation

Non-invasive, real-time temperature monitoring for thermal ablation allows for visualization of the temperature distribution for the tumor and ablation margin, helping ensure complete ablation of both the tumor and margin to reduce local tumor recurrences. Spectral CT thermometry detects temperature by relating physical density to temperature through the principle of thermal volumetric expansion, which describes the decrease in physical density with increased temperature. It has demonstrated feasibility, reproducibility, and sufficient temperature sensitivity critical for its clinical translation in liver-mimicking phantoms.

Non-invasive, real-time temperature monitoring for thermal ablation allows for visualization of the temperature distribution for the tumor and ablation margin, helping ensure complete ablation of both the tumor and margin to reduce local tumor recurrences. Spectral CT thermometry detects temperature by relating physical density to temperature through the principle of thermal volumetric expansion, which describes the decrease in physical density with increased temperature. It has demonstrated feasibility, reproducibility, and sufficient temperature sensitivity critical for its clinical translation in liver-mimicking phantoms.